Massachusetts Courtroom: Lindsay Clancy’s murder trial begins in Plymouth Superior Court with opening statements and the first witness, her ex-husband Patrick, as prosecutors argue she “meticulously” killed her three children and the defense pushes an insanity theory tied to postpartum psychosis and alleged overmedication. Local Business & Real Estate: Lender takeovers have moved in on South End life-science properties once tied to BioMed Realty, with lenders acquiring major office buildings after mortgage debt and lease shifts. State Tech & Lottery: The Massachusetts State Lottery goes live with a new online iLottery platform from Aristocrat Interactive, including exclusive eInstant options for players. Health & Biotech: Apnimed, a Massachusetts company, filed for an IPO to raise up to $160M for its sleep apnea pill, while ApsTron Science opened early access for a solar-assisted wearable called PhysioWatch. Public Safety: A hiker died after a medical emergency on New Hampshire’s Welch-Dickey trail, with rescuers using a helicopter evacuation. Culture: Boston Common hosts Commonwealth Shakespeare Company’s 30th-year run of “A Midsummer Night’s Dream.”